Polymer-metal complexes containing quarternary nitrogen...

Details Polymer-metal complexes containing quarternary nitrogen... Polymer-metal complexes containing quarternary nitrogen...

C - Chemistry, Metallurgy

08

F

402/7.3

C08F 8/42 (2006.01) A61K 31/785 (2006.01) A61K 31/80 (2006.01) C08G 73/02 (2006.01)

Patent

CA 1195046

Abstract of the Disclosure A novel polymer-metal complex containing quarternary nitrogen atoms, which is obtained by subjecting polyethylenepolyamine or polyethyleneimine to a reaction with a bifunctional compound represented by the formula Y-A-Z wherein Y and Z are same or different and are -CH2X, Image -CH(OH)CH2Xor -CH-CH2 group, respectively, A is a single bond, -(CH2)m-, -CH2-O-CH2-or -CH2-O(CH2)k-O-CH2-group, X is chlorine, bromine or iodine atom, m is an integral of 1 to 3, and k is an integral of 1 to 4, and then subjecting the resulting cross-linked polymer to a coordination of a polyvalent metal ion, a salt thereof, a process for the preparation thereof and a pharmaceutical agent comprising the same. -1-

414730

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