Polymeric benzyl carbonate-derivatives

Details Polymeric benzyl carbonate-derivatives Polymeric benzyl carbonate-derivatives

C - Chemistry, Metallurgy

07

C

C07C 69/708 (2006.01) A61K 47/48 (2006.01) A61P 7/00 (2006.01) C07C 69/63 (2006.01) C08G 65/333 (2006.01)

Patent

CA 2731184

The present invention relates to polymeric derivatives, which can be conjugated to an amino-containing drug to improve its in vivo properties. The polymeric derivative can subsequently be released to yield the drug in its native form. Methods of preparing and using these polymeric derivatives and drug conjugates are described.

La présente invention concerne des dérivés polymériques qui peuvent être conjugués à un médicament contenant un amino pour améliorer ses propriétés in vivo. Le dérivé polymérique peut, par la suite, être libéré pour produire le médicament dans sa forme dorigine. Des procédés de préparation et d'utilisation de ces conjugués de dérivés polymériques et de médicaments sont décrits.

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