Polymeric coatings and methods for cell attachment

Details Polymeric coatings and methods for cell attachment Polymeric coatings and methods for cell attachment

A - Human Necessities

61

L

A61L 27/38 (2006.01) A61L 27/34 (2006.01) A61L 27/40 (2006.01) A61L 31/10 (2006.01) A61L 31/12 (2006.01)

Patent

CA 2615868

The invention provides cell-adherent polymeric coatings for articles, the coating including a synthetic, non-biodegradable polymer having a plurality of pendent amine groups, wherein the polymer is covalently immobilized on the article via latent reactive groups. The invention also provides methods for the long-term attachment of cells using the polymeric coatings.

La présente invention concerne des revêtements polymères adhérant à la cellule destinés à des articles, ce revêtement comprenant un polymère synthétique non biodégradable possédant une pluralité de groupes amine pendants, ce polymère étant immobilisé de manière covalente sur l'article via des groupes réactifs latents. Cette invention concerne aussi des procédés de fixation à long terme de cellules au moyen de ces revêtements polymères.

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