Polymeric diffusion matrix containing a vasodilator

A - Human Necessities – 61 – J

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A61J 3/08 (2006.01) A61K 9/70 (2006.01) A61K 47/00 (2006.01)

Patent

CA 1163195

ABSTRACT A polymeric diffusion matrix containing a vasodilator is provided comprising from about 2 to about 60% of a polar plasticizer, e.g., glycerol, from about 2 to about 15% of a matrix component, e.g., polyvinylalcohol, from about 2 to about 10% of a water-soluble polymer with hydration sites, e.g., polyvinylpyrrolidone, which in combination with the remaining ingredients yields a matrix capable of sustained release of a vasodilator drug dispersed therein, and the balance water, the percentages being by weight.

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