Polymeric masking materials for spanning wound sites, and...

C - Chemistry – Metallurgy – 09 – K

Patent

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Details

C09K 3/10 (2006.01) C08G 75/14 (2006.01)

Patent

CA 2690624

One aspect of the present invention generally relates to methods of sealing a defect, wound or void using a two component system composed of masking material, which creates an anti-adhesion barrier, and a covering material. In certain embodiment, the covering material comprises an in situ polymerizing sealant. In certain embodiments, the in situ polymerizing sealant is a hydrogel which binds to the healthy tissue but remain unadhered to the area under the masking material. In certain embodiments, the masking material is also a hydrogel. In certain embodiments, normal biological processes may dissolve away the masking material leaving a protective cover of polymerized sealant over the wound site.

L'invention concerne de manière générale des procédés d'étanchéification d'un défaut, d'une plaie ou d'un vide en utilisant un système à deux composants constitué d'un matériau de masquage, créant une barrière anti-adhérence, et un matériau de recouvrement. Dans un certain mode de réalisation, le matériau de recouvrement est constitué d'un agent d'étanchéité à polymérisation in situ. Dans certains modes de réalisation, l'agent d'étanchéité à polymérisation in situ est un hydrogel qui se lie au tissu sain, mais reste hors d'adhérence avec la zone située sous le matériau de masquage. Dans certains modes de réalisation, le matériau de masquage est également un hydrogel. Dans certains modes de réalisation, des procédés biologiques normaux peuvent dissoudre le matériau de masquage en laissant un recouvrement de protection d'agent d'étanchéité polymérisé sur le site de plaie.

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