Polymeric matrices and their uses in pharmaceutical...

Details Polymeric matrices and their uses in pharmaceutical... Polymeric matrices and their uses in pharmaceutical...

A - Human Necessities

61

K

A61K 38/20 (2006.01) A61K 38/18 (2006.01) A61K 47/34 (2006.01)

Patent

CA 2474988

This invention provides pharmaceutical compositions comprising a pharmacologically active compound in polymeric matrices showing non-hydrolytic surface erosion. Specific novel poly(ethylene carbonate) polymers are also provided for more general use as matrix materials in sustained release compositions containing pharmacologically active compounds, as are methods of using IL-6 for treatment of conditions mediated by IL-1 and/or TNF.alpha., e.g., certain autoimmune and inflammatory conditions, as well as septic shock.

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