Polymeric orthoesters and process for making same

C - Chemistry – Metallurgy – 08 – G

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C08G 65/34 (2006.01) C08G 4/00 (2006.01)

Patent

CA 1112798

ARC 506 PATENT APPLICATION OF ALZA CORPORATION ALZA DOCKET NO.: ARC 506 TITLE: POLYMERIC ORTHOESTERS AND PROCESS FOR MAKING SAME ABSTRACT OF THE DISCLOSURE Polymeric orthoesters having a repeating mer of the general formula: Image wherein R1 and R2 may be various substituted or unsubsti- tuted hydrocarbon radicals and a is 2 or 3 are disclosed. These polymers are made by reacting a polyol of the formula (CH2OH)a R2(OH)3-a with an orthoester of the formula R1C(OR3)3 wherein R3 may be various hydrocarbon radicals to form a monomer and polymerizing the monomer in the presence of a polymerization catalyst. These orthroester polyrners find use as erodible coatings in a number of environments such as pesticides, preservatives and pharmaceuticals.

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