Polymeric reagents and polymer-biomolecule conjugates...

Details Polymeric reagents and polymer-biomolecule conjugates... Polymeric reagents and polymer-biomolecule conjugates...

C - Chemistry, Metallurgy

08

G

C08G 65/333 (2006.01) A61K 9/19 (2006.01) A61K 47/26 (2006.01) A61K 47/48 (2006.01) C08G 65/334 (2006.01)

Patent

CA 2510040

Polymeric reagents are provided comprising a urethane linkage occurring in a particular orientation between a water-soluble polymer and a reactive group. The polymeric reagents are useful for, among other things, forming polymer-active agent conjugates. Related methods, compositions, preparations, and so forth are also provided.

L'invention concerne des réactifs polymères comprenant un fragment d'atomes disposés selon un ordre spécifique, le fragment se trouvant entre un polymère hydrosoluble et un groupe réactif. Les réactifs polymères sont utilisés pour, entre autres, former des conjugués de polymères-principes actifs. Font également l'objet de cette invention des procédés, des compositions, des préparations connexes et autres.

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