Polymeric systems for controlled drug therapy

A - Human Necessities – 61 – K

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A61K 47/30 (2006.01) A61K 9/14 (2006.01)

Patent

CA 2536061

Polymeric compositions containing a high percentage of bound alkyl ether segments provide matrices and membranes for the controlled release of drugs and medicinal agents. The polymeric compositions are prepared by the polymerization of ethylenically unsaturated alkyl ether containing monomers. Copolymers of ethylenically unsaturated alkyl ether containing monomers with co-monomers are also disclosed. The drug loaded polymeric compositions of this invention find particular utility in the construction of controlled release devices.

L'invention concerne des compositions polymères contenant un pourcentage élevé de segments alkyle éther liés. Ces compositions sont utilisées dans la production de matrices et de membranes permettant la libération contrôlée de médicaments et d'agents médicinaux. Ces compositions polymères sont préparées par polymérisation de monomères contenant un alkyle éther éthyléniquement insaturé. L'invention concerne également des copolymères de monomères contenant un alkyle éther éthyléniquement insaturé et de co-monomères. Les compositions polymères à charge médicamenteuse selon l'invention sont particulièrement utiles dans la fabrication de dispositifs de libération contrôlée.

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