A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61F 2/06 (2006.01) A61K 31/436 (2006.01) A61K 47/12 (2006.01) A61K 47/30 (2006.01) A61L 27/14 (2006.01) A61L 27/34 (2006.01) A61L 27/54 (2006.01) A61L 31/10 (2006.01) A61L 31/16 (2006.01)
Patent
CA 2495081
Compositions of matter comprise linked pluralities of mTOR-binding molecules, such as rapamycin. The compositions may be directly polymerized or may comprise rapamycin or other mTOR-binding molecules covalently or non- covalently attached to a backbone molecule. The compositions may be bound to vascular prostheses and other implantable devices in order to inhibit hyperplasia or for other therapeutic purposes.
La présente invention concerne des compositions de matière qui comprennent des pluralités reliées de molécules de liaison TORm, telles que la rapamycine. Ces compositions peuvent être directement polymérisées ou peuvent comprendre de la rapamycine ou d'autres molécules de liaison TORm fixées par covalence ou non à une molécule squelette. Ces compositions peuvent être liées à des prothèses vasculaires et à d'autres dispositifs implantables de façon à inhiber une hyperplasie ou à d'autres fins thérapeutiques.
Cifra Pamela N.
Dake Michael D.
Nezhat Camran
Razavi Mahmood
Waugh Jacob
Borden Ladner Gervais Llp
Polycord Inc.
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