C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/805 (2006.01) A61K 35/14 (2006.01) A61K 38/16 (2006.01) A61K 38/42 (2006.01) A61P 7/00 (2006.01) C07K 1/02 (2006.01)
Patent
CA 2512169
A substantially tetramer free hemoglobin solution and a method for producing a substantially tetramer free hemoglobin solution. The method includes polymerizing a solution of hemoglobin, treating the polymerized hemoglobin solution to partially degrade the polymer to tetramer and removing tetramer from the hemoglobin solution.
L'invention concerne une solution d'hémoglobine sensiblement exempte de tétramères et un procédé pour fabriquer une solution d'hémoglobine sensiblement exempte de tétramères. Le procédé consiste à polymériser une solution d'hémoglobine, à traiter la solution d'hémoglobine polymérisée pour décomposer partiellement le polymère en tétramère et à évacuer le tétramère de la solution d'hémoglobine.
Avella Anthony
Dewoskin Richard E.
Doubleday Marc D.
Northfield Laboratories Inc.
Smart & Biggar
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