C - Chemistry – Metallurgy – 08 – F
Patent
C - Chemistry, Metallurgy
08
F
402/405, 167/10.
C08F 226/06 (2006.01) A01N 43/36 (2006.01) A61K 31/785 (2006.01) A61L 2/18 (2006.01) A61L 12/14 (2006.01) C08G 73/02 (2006.01) C08G 73/06 (2006.01)
Patent
CA 1208844
A B S T R A C T Polymers containing 55 to 90% of units of the formula (A): Image (A) wherein R is a hydrogen atom or an alkyl group of 1 to 3 carbon atoms; and 10 to 45% of units of the formula (B) and (C): Image (B) wherein R2 is a hydrogen group of 5 to 19 carbon atoms, for example n-C11H23, R3 is a hydrogen atom or an alkyl group of 1 to 3 carbon atoms, R4 is a hydrocarbon group of 5 to 19 carbon atoms, for example n-C11H23 and X- is an anion and which contain at least 10% of units of formula (C) and are free from polymeric species having a molecular weight of less than 10,000 are described. The polymers possess antimicrobial activity agains common pathogens. Isotonic aqueous solutions containing 0.002 to 0.025% of the polymer are suitable for the sterilisation of contact lenses for example by immersion of the lens in the solution overnight. Hydrophilic ointments containing from 0.002 to 0.25% of the polymer are suitable for the treatment of bacterial infection of lesions of the skin such as burns and ulcers.
392125
Borden Ladner Gervais Llp
Smith And Nephew Associated Companies Limited
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