Polymorph forms of...

C - Chemistry – Metallurgy – 07 – D

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C07D 417/14 (2006.01) A61K 31/427 (2006.01) A61P 3/04 (2006.01)

Patent

CA 2699472

New crystalline forms of (S)-2-((4-benzo- furanyl)carbonylamino methyl)-1-((4-(2-methyl-5-(4-fluo- rophenyl))thiazolyl)carbonyl)piperidine, methods for their preparation and use in medicine as orexin receptor antagonist.

La présente invention concerne de nouvelles formes cristallines de (S)-2-((4-benzofuranyl)carbonylaminométhyl)-1-((4-(2-méthyl-5-(4-fluorophényl))thiazolyl)carbonyl)pipéridine, des procédés permettant leur préparation et leur utilisation médicale en tant qu'antagoniste du récepteur de l'orexine.

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