Polymorph forms of (2s) - (4e) -n-methyl-5-...

Details Polymorph forms of (2s) - (4e) -n-methyl-5-... Polymorph forms of (2s) - (4e) -n-methyl-5-...

C - Chemistry, Metallurgy

07

D

C07D 213/63 (2006.01) A61K 31/44 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2649961

Polymorph forms of (2S)-(4E)-N-methyl-5-[3-(5-isopropoxypyridin)yl]-4- penten-2-amine p-hydroxybenzoate, and methods for their preparation, pharmaceutical composition containing said polymorph(s) and use, are disclosed. The polymorphs can be administered to patients susceptible to or suffering from conditions and disorders, such as central nervous system disorders, to treat and/or prevent such disorders.

L'invention concerne des formes polymorphes de (2S)-(4E)-N-méthyl-5-[3-(5-isopropoxypyridin)yl]-4- penten-2-amine p-hydroxybenzoate et des procédés de préparation de ces formes, une composition pharmaceutique contenant ces polymorphes et l'utilisation de celle-ci. Ces polymorphes peuvent être administrés à des patients susceptibles de souffrir ou soufrant de pathologies ou de troubles, tels que des troubles du système nerveux central, afin de traiter et/ou prévenir ces troubles.

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