Polymorph of atomoxetine hydrochloride in crystalline form

Details Polymorph of atomoxetine hydrochloride in crystalline form Polymorph of atomoxetine hydrochloride in crystalline form

C - Chemistry, Metallurgy

07

C

C07C 217/48 (2006.01) C07C 213/10 (2006.01)

Patent

CA 2633229

The present invention discloses a process for the preparation of atomoxetine hydrochloride in a pure crystalline form, characterised by an XRPD spectrum as in (Fig 1). It is also object of the present invention to provide methods to obtain pure atomoxetine hydrochloride without the use of methylene chloride.

La présente invention concerne un procédé pour la préparation de chlorhydrate d'atomoxétine sous une forme cristalline pure, caractérisé par un spectre XRPD comme décrit à la figure 1. La présente invention concerne en outre des procédés pour obtenir du chlorhydrate d'atomoxétine pur sans utilisation de dichlorométhane.

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