Polymorph of zopolrestat monohydrate

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 417/06 (2006.01) A61K 31/50 (2006.01)

Patent

CA 2280590

This invention relates to zopolrestat monohydrate and polymorphs thereof. This invention also relates to processes for preparing zopolrestat monohydrate, for preparing polymorphs thereof and for preparing anhydrous zopolrestat. This invention also relates to compositions comprising zopolrestat monohydrate and to methods of using zopolrestat monohydrate and compositions thereof to treat diabetic complications such as diabetic cataracts, diabetic retinopathy or diabetic neuropathy, lower blood lipid levels or blood uric level.

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