Polymorphic form of rasagiline mesylate

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 211/42 (2006.01) A61K 31/135 (2006.01) A61P 25/16 (2006.01) C07C 309/04 (2006.01)

Patent

CA 2731164

The present invention relates to a novel crystalline form of rasagiline mesylate and a pure form of rasagiline mesylate and processes for their preparation. Further, the invention relates to pharmaceutical compositions comprising said forms and use of said compositions in the treatment of patients suffering from Parkinson's Disease, dementia, Alzheimer's Disease, depression, hyperactive syndrome, stroke, brain ischemia, neurotrauma, schizophrenia and multiple sclerosis.

La présente invention concerne une nouvelle forme cristalline de mésilate de rasagiline et une forme pure de mésilate de rasagiline ainsi que leurs procédés de préparation. La présente invention concerne également des compositions pharmaceutiques comportant lesdites formes et lutilisation desdites compositions dans le traitement de patients souffrant de la maladie de Parkinson, de démence, de la maladie dAlzheimer, de dépression, du syndrome hyperactif, d'un accident vasculaire cérébral, dischémie du cerveau, d'un traumatisme neurologique, de schizophrénie et de la sclérose en plaques.

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