C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 295/08 (2006.01) A61K 31/495 (2006.01) C07D 295/088 (2006.01)
Patent
CA 2488114
The present invention relates to crystalline and amorphous forms of dextrorotatory dihydrochloride salt of cetirizine, the process for the preparation thereof and compositions containing the same. The invention also relates to the crystalline and amorphous forms of levorotatory dihydrochloride salt of cetirizine, the process for the preparation thereof and compositions containing the same. Both crystalline and amorphous salt forms of cetirizine dihydrochloride are suitable for pharmaceutical purposes in the treatment of allergies, including ailments such as chronic and acute allergic rhinitis, allergic conjunctivitis, pruritus, urticaria and the like.
La présente invention concerne des formes cristalline et amorphe de sels de dihydrochlorure de cétirizine à base de dextrose, le processus de préparation de celles-ci et des compositions contenant ces formes. Cette invention concerne aussi des formes cristalline et amorphe de sel de dihydrochlorure de cétirizine à base de lévulose, le processus de préparation de celles-ci et des compositions contenant ces formes. Les deux formes cristalline et amorphe de ces sels de dihydrochlorure de cétirizine conviennent pour des fins pharmaceutiques dans le traitement d'allergies, notamment des malaises tels que la rhinite allergique chronique et aiguë, la conjonctivite allergique, le prurit, l'urticaire et d'autres pathologies d'origine allergique.
Joga Rajender
Reddy Manne Satyanarayana
Srinivasan Thirumalai Rajan
Uppala Venkata Bhaskara Rao
Vaddadi Pattabhi Ramayya
Dr. Reddy's Laboratories Inc.
Dr. Reddy's Laboratories Limited
Marks & Clerk
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