C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 489/08 (2006.01) A61K 31/485 (2006.01) A61P 25/32 (2006.01)
Patent
CA 2527693
This invention relates to the discovery of novel polymorphic forms of naltrexone, including solvates, hydrates, anhydrous and other crystalline forms and combinations thereof. These novel forms of naltrexone impart advantages in pharmaceutical formulations incorporating them, including sustained release, or long acting, formulations.
L'invention concerne de nouvelles formes polymorphes de naltrexone, y compris des solvates, des hydrates, des formes anhydres et cristallines et des combinaisons de celles-ci. Ces nouvelles formes de naltrexone confèrent des avantages aux formulations pharmaceutiques incorporant celles-ci, y compris les formulations à libération prolongée ou à action prolongée.
Brittain Harry G.
Dickason David A.
Hotz Joyce
Lyons Shawn L.
Ramstack J. Michael
Alkermes Inc.
Alkermes Controlled Therapeutics II
Gowling Lafleur Henderson Llp
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