Polymorphic markers of prostate carcinoma tumor antigen-1...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A01K 67/027 (2006.01) C07K 7/00 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/30 (2006.01) C12Q 1/68 (2006.01) G11B 23/00 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2328500

The invention concerns the genomic sequence and cDNA sequences of the PCTA-1 gene. The invention also concerns biallelic markers of the PCTA-1 gene and the association established between these markers and prostate cancer. The invention provides means to determine the predisposition of individuals to prostate cancer as well as means for the diagnosis of prostate cancer and for the prognosis/detection of an eventual treatment response to agents acting against prostate cancer.

La présente invention concerne la séquence génomique et les séquences d'ADNc du gène PCTA-1. L'invention se rapporte également à des marqueurs bialléliques du gène PCTA-1 et à l'association établie entre ces marqueurs et le cancer de la prostate. L'invention concerne un moyen permettant de déterminer la prédisposition d'un individu au cancer de la prostate, et un moyen permettant de diagnostiquer le cancer de la prostate et de pronostiquer et/ou de détecter une réponse de traitement éventuelle à des agents agissant contre le cancer de la prostate.

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