Polymorphisms predictive of platinum-coordinating...

Details Polymorphisms predictive of platinum-coordinating... Polymorphisms predictive of platinum-coordinating...

C - Chemistry, Metallurgy

04

B

C04B 40/06 (2006.01) A61K 33/24 (2006.01) A61K 45/00 (2006.01) C07H 21/00 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) C40B 30/00 (2006.01) C40B 30/04 (2006.01)

Patent

CA 2740950

Methods of determining a subj ecf s ototoxicity risk from administration of platmum-coordmatmg compounds having an ototoxicity risk, methods of administering a platmum-coordmatmg compound having an ototoxicity risk and oligonucleotides, peptide nucleic acids, arrays and addressable collections for performing embodiments of the methods are provided herein.

L'invention porte sur des procédés de détermination d'un risque d'ototoxicité d'un sujet à partir de l'administration de composés de coordination du platine présentant un risque d'ototoxicité, sur des procédés d'administration d'un composé de coordination du platine présentant un risque d'ototoxicité et sur des oligonucléotides, sur des acides nucléiques codant pour des peptides, sur des réseaux et des ensembles adressables pour mettre en uvre des modes de réalisation des procédés.

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