C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/14 (2006.01) A61K 31/42 (2006.01) A61P 9/00 (2006.01)
Patent
CA 2644134
N-(4-chloro-3-methyl-5-isoxazolyl)-2-[2-methyl-4,5-(methylenedioxy)phenyl- acetyl]thiophene-3-sulfonamide,, sodium salt, is provided herein in the form of three polymorphs (Forms A, B and C). Forms A, B and C are specified by the peaks in their X-ray powder diffraction patterns, their absorption peaks in their infrared absorption spectra, their peaks in their Raman spectra and their melting points.
La présente invention concerne le sel de sodium de N-(4-chloro-3-méthyl-5-isoxazolyl)-2-[2-méthyl-4,5-(méthylènedioxy)phényl-acétyl]thiophène-3-sulfonamide sous la forme de trois polymorphes (formes A, B et C). Les formes A, B et C sont caractérisées par les pics sur leurs diagrammes de diffraction de rayons X en poudre, leurs pics d'absorption sur leurs spectres d'absorption IR, leurs pics sur leurs spectres de Raman et leurs températures de fusion.
Hansen Tim
Reichwein John F.
Encysive Pharmaceuticals Inc.
Smart & Biggar
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