C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 217/48 (2006.01) C07C 213/10 (2006.01)
Patent
CA 2568629
The present invention provides novel crystalline polymorph forms of atomoxetine hydrochloride denominated Forms B and C and methods for their preparation, as well as methods for the preparation of Form A. The present invention provides pharmaceutical compositions that comprise atomoxetine hydrochloride Form B, Form C, or mixtures thereof that can be used to treat attention deficit/ hyperactivity disorder.
L'invention porte sur de nouvelles formes polymorphes cristallines du chlorhydrate d'atomoxétine dénommées formes B et C et sur des procédés de préparation de ces dernières, et sur des procédés de préparation de la forme A. L'invention concerne des compositions pharmaceutiques comprenant la forme B du chlorhydrate d'atomoxétine, la forme C du chlorhydrate d'atomoxétine ou des mélanges de ces dernières, qui peuvent être utilisées pour traiter les troubles d'hyperactivité avec déficit d'attention.
Aronhime Judith
Bianchi Stefano
Castelli Eugenio
Daverio Paola
Kovacsne-Mezei Adrienne
Heenan Blaikie Llp
Teva Pharmaceutical Fine Chemicals S.r.l.
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