Polymorphs of bicifadine hydrochloride

Details Polymorphs of bicifadine hydrochloride Polymorphs of bicifadine hydrochloride

C - Chemistry, Metallurgy

07

D

C07D 209/52 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2504732

A new polymorphic crystalline form of bicifadine hydrochloride, designated form B, which is more thermodynamically stable than the previously known polymorphic form of bicifadine hydrochloride, designated as form A, methods for preparing said crystalline form B and pharmaceutical compositions containing said crystalline form B.

L'invention concerne une nouvelle forme cristalline polymorphe du chlorhydrate de bicifadine, dite forme B, plus stable au plan thermodynamique que les formes polymorphes du chlorhydrate de bicifadine connues jusqu'à maintenant, dites forme A. L'invention concerne également des méthodes destinées à la préparation de cette forme cristalline B, ainsi que des compositions pharmaceutiques contenant ladite forme cristalline B.

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