Polymorphs of darunavir

Details Polymorphs of darunavir Polymorphs of darunavir

C - Chemistry, Metallurgy

07

D

C07D 493/04 (2006.01) A61K 31/635 (2006.01) A61P 31/18 (2006.01)

Patent

CA 2750774

The present invention provides new pseudopolymorphic forms of darunavir as well as a novel amorphous form of darunavir, pharmaceutical compositions comprising these compounds, methods for their preparation and use thereof in treating retroviral infections, in particular, HIV infection.

La présente invention porte sur de nouvelles formes pseudopolymorphiques de darunavir, ainsi que sur une nouvelle forme amorphe de darunavir, sur des compositions pharmaceutiques comprenant ces composés, sur des procédés pour leur préparation et pour l'utilisation de ceux-ci dans le traitement d'infections rétrovirales, en particulier l'infection par le VIH.

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