Polymorphs of prostaglandin agonists and methods for making...

C - Chemistry – Metallurgy – 07 – D

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C07D 213/71 (2006.01) A61K 31/435 (2006.01)

Patent

CA 2697950

The present invention relates to polymorphic crystalline forms or a non- crystalline form or amorphous of the compound (3-(((4-tert-butyl-benzyl)-(pyridine- 3-sulfonyl)-amino)-methyl)- phenoxy)-acetic acid sodium salt or a hydrate thereof together with processes for preparing, methods for using, and pharmaceutical compositions containing the same. The invention also relates to substantially pure polymorphic crystalline forms or a non- crystalline form or amorphous form of (3-(((4-tert-butyl-ben-zyl)-(pyridine-3-sulfonyl)-amino)-methyl)-phenoxy)- acetic acid sodium salt or a hydrate thereof.

La présente invention concerne des formes cristallines polymorphes ou une forme non cristalline ou amorphe du composé sel de sodium d'acide acétique (3-(((4-tert-butyl-benzyl)-(pyridine- 3-sulfonyl)-amino)-méthyl)-phénoxy) ou un hydrate de celui-ci, ainsi que des procédés de préparation de celles-ci, des procédés d'utilisation de celles-ci et des compositions pharmaceutiques les contenant. L'invention concerne également des formes cristallines polymorphes sensiblement pures ou une forme non cristalline ou amorphe du sel de sodium d'acide acétique (3- (((4-tert-butyl-benzyl)-(pyridine-3-sulfonyl)-amino)-méthyl)-phénoxy) ou un hydrate de celui-ci.

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