Polymorphs of zaleplon and methods for the preparation thereof

Details Polymorphs of zaleplon and methods for the preparation thereof Polymorphs of zaleplon and methods for the preparation thereof

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 21/02 (2006.01) A61P 25/08 (2006.01) A61P 25/20 (2006.01) A61P 25/22 (2006.01) C07D 231/00 (2006.01) C07D 239/00 (2006.01)

Patent

CA 2417875

This invention relates to novel crystalline polymorphic forms of zaleplon (N- [3-(3-cyanopyrazolo[1,5a]pyrimidin-7-yl)phenyl]-N-ethylacetamide), methods for the preparation thereof, and their uses as anxiolytic, antiepileptic, and sedative-hypnotic agents and skeletal muscle relaxants.

L'invention concerne de nouvelles formes cristallines polymorphes de zaleplon (N-[3-(3-cyanopyrazolo[1,5a]pyrimidine-7-yl)phényl]-N-éthylacétamide), des procédés de préparation de ceux-ci, et leur utilisation comme agents anxiolytiques, anti-épileptiques et sédatifs-hypnotiques, et comme relaxants des muscles squelettiques.

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