Polynucleotide containing a phosphate mimetic

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 21/00 (2006.01)

Patent

CA 2627208

The present invention concerns modified oligonucleotides and processes for their production wherein these oligonucleotides contain at least once the structure P = N - Acc where Ace is an electron acceptor or an electron acceptor substituted with a residue R and R is any organic substituent.

L'invention concerne des oligonucléotides modifiés et des procédés de production de ceux-ci dans lesquels lesdits oligonucléotides contiennent au moins une fois la structure P = N Acc, dans laquelle Acc est un accepteur d'électrons ou un accepteur d'électrons substitué par un résidu R, R étant un substituant organique quelconque.

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