Polynucleotide encoding a novel human g-protein coupled...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) C07K 14/705 (2006.01) C12N 5/06 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2440058

The present invention provides novel polynucleotides encoding HGPRBMY27 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel HGPRBMY27 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

L'invention concerne de nouveaux polynucléotides codant des polypeptides HGPRBMY27, des fragments et des homologues de ceux-ci. L'invention concerne également des vecteurs, des cellules hôtes, des anticorps et des procédés de synthèse et de recombinaison permettant de produire lesdits polypeptides. Cette invention concerne également des procédés diagnostiques et thérapeutiques servant à appliquer ces nouveaux polypeptides HGPRBMY27 à un diagnostic, traitement, et/ou à la prévention de différentes maladies et/ou troubles associés à ces polypeptides. Cette invention concerne également des procédés de dépistage permettant d'identifier des agonistes et des antagonistes des polynucléotides et polypeptides de la présente invention.

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