C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/15 (2006.01) A61K 31/7088 (2006.01) A61K 38/57 (2006.01) A61K 48/00 (2006.01) A61P 9/00 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01) C07K 14/81 (2006.01) C07K 16/38 (2006.01) C12P 19/34 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G06F 17/50 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2429179
The present invention provides novel polynucleotides encoding LSI-01 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention furtherrelates to diagnostic and therapeutic methods for applying these novel LSI-01 polypeptides to the diagnosis, treatment, and/or prevention of various diseas and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
La présente invention concerne des nouveaux polynucléotides codant pour des polypeptides LSI-01, des fragments et des homologues desdits polypeptides. L'invention concerne également des vecteurs, des cellules hôtes, des anticorps et des méthodes de recombinaison et des méthodes synthétiques destinées à la production de ces polypeptides. Ladite invention se rapporte en outre à des méthodes diagnostiques et thérapeutiques permettant d'appliquer ces nouveaux polypeptides LSI-01 au diagnostic, au traitement et/ou à la prévention de maladies et/ou de troubles divers associés auxdits polypeptides. Elle porte enfin sur des méthodes de criblage destinées à identifier des agonistes et des antagonistes des polynucléotides et des polypeptides susmentionnés.
Bassolino Donna A.
Chen Jian
Cheney Daniel L.
Duclos Frank
Feder John N.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
LandOfFree
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