Polynucleotide probes and a method for their preparation

C - Chemistry – Metallurgy – 07 – H

Patent

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195/1.12

C07H 21/04 (2006.01) C07H 21/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 1315222

ABSTRACT This invention relates to polynucleotide probes and a method for their preparation. The method involves displacing the 4-amino group of a cytosine base with a hydrazide compound and attaching a reporting moiety to the hydrazide compound. The cytosine base can be free or of a nucleoside, nucleotide, oligonucleotide, or polynucleotide.

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