Polynucleotide sequence detection assays and analysis

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) C12N 1/00 (2006.01) G01N 27/26 (2006.01)

Patent

CA 2505687

Methods and software for associating mobility probes with target macromolecules are discussed. By encoding the identities of macromolecules of interest with a universal set of tag portions complementary to a universal set of mobility probes, reactions varying in their input starting material may be identified using the same universal set of mobility probes. This allows the universal collection of mobility probes to be used in a target macromolecule- independent manner. Software is used to decode the associations between the mobility probes and a given target macromolecular identity.

L'invention concerne des méthodes et un logiciel permettant d'associer des sondes à mobilité à des macromolécules cibles. Le codage des identités des macromolécules d'intérêt avec un ensemble universel de parties étiquettes complémentaire d'un ensemble universel de sondes à mobilité permet d'identifier des réactions présentant différentes matières de départ au moyen du même ensemble de sondes à mobilité. On peut ainsi utiliser une collection universelle de sondes à mobilité indépendamment des macromolécules cibles. On utilise un logiciel pour décoder les associations entre les sondes à mobilité et une identité macromoléculaire cible donnée.

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