A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 31/70 (2006.01) A61K 39/295 (2006.01) C07K 14/015 (2006.01) C07K 14/03 (2006.01) C07K 14/08 (2006.01) C07K 14/11 (2006.01) C07K 14/18 (2006.01) C07K 14/285 (2006.01)
Patent
CA 2261346
A porcine vaccine formula for treating porcine respiratory and reproductive disease, including at least three polynucleotide vaccine valencies that each include a plasmid containing a porcine pathogen valency gene capable of being expressed in vivo in host cells. Said valencies are selected from two groups which consist of Aujeszky's disease virus, swine influenza virus, mysterious swine disease virus, parvovirus disease virus, pest disease virus, and bacteria causing actinobacillosis. Said plasmids include one or more genes per valency, and said genes are selected from the group which consists of gB and gD for Aujeszky's disease virus, HA, NP and N for swine influenza virus, E, N, ORF3 and M for mysterious swine disease virus, VP2 for parvovirus disease virus, E1 and E2 for pest disease virus, and apxI, apxII and apxIII for actinobacillosis virus.
La formule de vaccin porcin contre la pathologie respiratoire et/ou de reproduction des porcs, comprend au moins 3 valences de vaccin polynucléotidique comprenant chacune un plasmide intégrant, de manière à exprimer in vivo dans les cellules hôtes, un gène d'une valence de pathogène porcin, ces valences étant choisies parmi deux groupes consistant en virus de la maladie d'Aujeszky, virus de la grippe porcine, mystérieuse du porc, virus de la grippe porcine, virus de la maladie mystérieuse du porc, virus de la parvovirose, virus de la pestivirose et bactéries responsables de l'actinobacillose, les plasmides comprenant, pour chaque valence, un ou plusieurs des gènes choisis parmi le groupe consistant en gB et gD pour le virus de la maladie d'Aujeszky, HA, NP, N pour le virus de la grippe porcine, E, N, ORF3, M pour le virus de la maladie mystérieuse, VP2 pour le virus de la parvovirose, E1, E2 pour le virus de la pestivirose et apxI, apxII et apxIII pour le virus de l'actinobacillose.
Audonnet Jean-Christophe
Baudu Philippe
Bouchardon Annabelle
Riviere Michel
Merial
Smart & Biggar
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