A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 31/70 (2006.01) A61K 39/295 (2006.01) C07K 14/06 (2006.01) C07K 14/115 (2006.01) C07K 14/135 (2006.01) C07K 14/18 (2006.01)
Patent
CA 2260855
A bovine vaccine formula for treating bovine respiratory disease is disclosed. Said formula includes at least three polynucleotide vaccine valencies that each include a plasmid containing a bovine respiratory disease valency gene capable of being expressed in vivo in host cells. Said valencies are selected from the group which consists of bovine herpes virus, bovine respiratory syncytial virus, mucosal disease virus and parainfluenza virus type 3. The plasmids include one or more genes per valency, and said genes are selected from the group which consists of gB and gD for bovine herpes virus, F and G for bovine respiratory syncytial virus, E2, C + E1 + E2 and E1 + E2 for mucosal disease virus and HN and F for parainfluenza virus type 3.
La formule de vaccin bovin contre la pathologie respiratoire des bovins, comprend au moins trois valences de vaccin polynucléotidique comprenant chacune un plasmide intégrant, de manière à l'exprimer in vivo dans les cellules hôtes, un gène d'une valence de pathogène respiratoire bovin, ces valences étant choisies parmi le groupe consistant en virus herpès bovin, virus respiratoire syncitial bovin, virus de la maladie des muqueuses et virus parainfluenza de type 3, les plasmides comprenant, pour chaque valence, un ou plusieurs des gènes choisis parmi le groupe consistant en gB et gD pour le virus herpès bovin, F et G pour le virus respiratoire syncitial bovin, E2, C + E1 + E2 et E1 + E2 pour le virus de la maladie des muqueuses, HN et F pour le virus parainfluenza de type 3.
Audonnet Jean-Christophe
Baudu Philippe
Bouchardon Annabelle
Riviere Michel
Merial
Smart & Biggar
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