Polynucleotides and polypeptides coded by said...

C - Chemistry – Metallurgy – 07 – K

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C07K 14/36 (2006.01) C12N 15/68 (2006.01) C12P 21/04 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2490517

The invention concerns novel isolated natural or synthetic polynucleotides and polypeptides coded by said polynucleotides, involved in the synthesis of diketopiperazine derivatives, vectors comprising said polynucleotides, micro-organisms transformed with said polynucleotides, uses of said polynucleotides and said polypeptides, as well as methods for the synthesis of diketopiperazine derivatives, including cyclodipeptides and diketopiperazine derivatives 3- and 6- substituted by .alpha.,.beta.-unsaturated amino acid side chains.

La présente Invention est relative à de nouveaux polynucléotides isolés, naturels ou synthétiques, et aux polypeptides codés par lesdits polynucléotides, impliqués dans la synthèse des dérivés des dicétopipérazines, aux vecteurs comprenant lesdits polynucléotides, aux microorganismes transformés avec lesdits polynucléotides, aux applications desdits polynucléotides et desdits polypeptides, ainsi qu'à des procédés de synthèse de dérivés des dicétopipérazines dont des cyclodipeptides et des dicétopipérazines substituées en positions 3 et 6 par des chaînes latérales d'acides aminés .alpha.,.beta.-insaturées.

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