Polynucleotides and polypeptides encoded thereby

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 14/515 (2006.01) C07K 14/575 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2377263

The invention provides novel polypeptides, designated herein as SECX polypeptides, as well as polynucleotides encoding SECX polypeptides. Also provided are antibodies that immunospecifically-bind to SECX polypeptide or polynucleotide, or derivatives, variants, mutants, or fragments thereof. The invention additionally provides methods in which the SECX polypeptide, polynucleotide, and antibody are used in the detection, prevention, and treatment of a broad range of pathological states.

La présente invention concerne de nouveaux polypeptides, désignés polypeptides SECX par la suite, ainsi que des polynucléotides codant pour lesdits polypeptides SECX. L'invention concerne également des anticorps de liaison immunospécifique audit polypeptide ou polynucléotide SECX, ou aux dérivés, variants, mutants, ou fragments de ceux-ci. L'invention concerne en outre des procédés dans lesquels les polypeptides, polynucléotides, et anticorps SECX sont utilisés pour la détection, la prévention, et le traitement d'une grande variété de conditions pathologiques.

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