Polynucleotides and their applications in diagnostics

Details Polynucleotides and their applications in diagnostics Polynucleotides and their applications in diagnostics

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) C07K 14/47 (2006.01) C12N 15/12 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2358697

CASB611, CASB500, CASB501, CASB502, CASB505, or CASB507 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing CASB611, CASB500, CASB501, CASB502, CASB505, or CASB507 polypeptides and polynucleotides in diagnostics, and vaccines for prophylactic and therapeutic treatment of cancers, particularly colon cancers, autoimmune diseases, and related conditions.

Cette invention a trait à des polypeptides et à des polynucléotides CASB611, CASB500, CASB501, CASB502, CASB505 ou CASB507 ainsi qu'à des procédés de production de ceux-ci grâce à des techniques de recombinaison. Elle porte également sur des méthodes d'utilisation des polypeptides et des polynucléotides CASB611, CASB500, CASB501, CASB502, CASB505 ou CASB507 pour l'établissement de diagnostics et la préparation de vaccins destinés à prévenir ou traiter des cancers, notamment des cancers du côlon, ainsi que des maladies auto-immunes et des états pathologiques apparentés.

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