Polynucleotides encoding antigenic hiv type c polypeptides,...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/48 (2006.01) A61K 31/7088 (2006.01) A61K 39/21 (2006.01) A61K 48/00 (2006.01) A61P 31/18 (2006.01) C07K 14/16 (2006.01) C12N 5/00 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C12N 15/70 (2006.01) C12N 15/74 (2006.01) C12N 15/867 (2006.01) C12P 21/02 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2452015

The present invention relates to polynucleotides encoding immunogenic HIV polypeptides. Uses of the polynucleotides in applications including immunization, generation of packaging cell lines, and production of HIV polypeptides are also described. Polynucleotides encoding antigenic HIV polypeptides are described, as are uses of these polynucleotides and polypeptide products therefrom, including formulations of immunogenic compositions and uses thereof.

L'invention se rapporte à des polynucléotides codant des polypeptides du VIH immunogènes. L'invention se rapporte également à des utilisations de polynucléotides dans des applications, notamment l'immunisation, la génération de lignées cellulaires d'encapsidation, et la production de polypeptides du VIH. En outre, l'invention concerne des polynucléotides codant des polypeptides du VIH antigéniques, et des utilisations de ces polynucléotides et des produits polypeptidiques dérivés de ces polynucléotides, notamment des formulations de préparations immunogènes et leurs utilisations.

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