Polynucleotides encoding isoprenoid modifying enzymes and...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/53 (2006.01) A01H 5/00 (2006.01) C12N 9/02 (2006.01) C12N 15/63 (2006.01) C12P 5/00 (2006.01) C12P 7/02 (2006.01) C12P 23/00 (2006.01) C12N 15/82 (2006.01)

Patent

CA 2613469

The present invention provides isolated nucleic acids comprising nucleotide sequences encoding isoprenoid modifying enzymes, as well as recombinant vectors comprising the nucleic acids. The present invention further provides genetically modified host cells comprising a subject nucleic acid or recombinant vector. The present invention further provides a transgenic plant comprising a subject nucleic acid. The present invention further provides methods of producing an isoprenoid compound, the method generally involving culturing a subject genetically modified host cell under conditions that permit synthesis of an isoprenoid compound modifying enzyme encoded by a subject nucleic acid.

La présente invention concerne des acides nucléiques isolés comprenant des séquences nucléotidiques codant pour des enzymes de modification d'isoprénoïdes, ainsi que des vecteurs recombinés comprenant ces acides nucléiques. La présente invention concerne également des cellules hôtes génétiquement modifiées comprenant un acide nucléique ou un vecteur recombiné tel que mentionné ci-dessus. Elle concerne en outre une plante transgénique comprenant un acide nucléique tel que mentionné ci-dessus. Par ailleurs, la présente invention se rapporte à des méthodes destinées à produire un composé isoprénoïde, cette méthode consistant généralement à cultiver une cellule hôte génétiquement modifiée telle que mentionnée ci-dessus dans des conditions permettant la synthèse d'une enzyme de modification de composé isoprénoïde codée par un acide nucléique.

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