Polynucleotides encoding members of the human b lymphocyte...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2383788

The present invention provides novel isolated BLAA polynucleotides and the membrane-associated or secreted polypeptides encoded by the BLAA polynucleotides. Also provided are the antibodies that immunospecifically bind to a BLAA polypeptide or any derivative, variant, mutant or fragment of the BLAA polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the BLAA polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.

La présente invention concerne de nouveaux polynucléotides BLAA isolés et les polypeptides associés à la membrane ou sécrétés par la membrane codés par les polynucléotides BLAA. L'invention concerne également les anticorps se fixant de manière immunospécifique à un polypeptide BLAA ou n'importe quel dérivé, variant, mutant ou fragment du polypeptide, polynucléotide ou anticorps BLAA. De plus, l'invention concerne des méthodes dans lesquelles le polypeptide, le polynucléotide et les anticorps BLAA sont utilisés dans la détection et le traitement d'une large gamme d'états pathologiques, de même que dans d'autres utilisations.

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