Polyol derivatives processes for preparing the same and...

Details Polyol derivatives processes for preparing the same and... Polyol derivatives processes for preparing the same and...

C - Chemistry, Metallurgy

07

C

260/352.1, 260/4

C07C 69/22 (2006.01) C07C 69/708 (2006.01) C07D 303/16 (2006.01) C07D 317/12 (2006.01) C07D 317/20 (2006.01) C07D 317/24 (2006.01) C07D 317/30 (2006.01) C07D 317/72 (2006.01) C07D 319/06 (2006.01)

Patent

CA 1162928

ABSTRACT OF THE DISCLOSURE: The invention is concerned with mono-, di-, tri- and tetra-esters derived from an acid of the general formula: R-OH (I) in which R represents an acyl radical of the general formula: Image in which n represents 0 or 1, m represents 0, 1,2 or 3, R1 and R2 each represent ethyl, n-propyl or n-butyl, R3 represents hydrogen, methyl or n-propyl or R1 and R2 when they are taken together represent pentamethylene radical and R3 represents methyl and an alcohol selected from the group consisting of glycerol, 1,2-propanediol, 1,3-propanediol, 1,3-butanediol, 1,4-butanediol, 1,2,4-butanetriol, 2-buten-1,4-diol, 2-butyn- 1,4-diol, diethyleneglycol, thiodiglycol, N-R-substituted- diethanolamine, trimethylolpropane, pentaerythritol or an alcohol of the general formula: Image (II) in which p represents 0 or 1, R4 represents methyl, R5 represents methyl, ethyl, 2-methyl-butyl or R4 and R5, when they are taken together represent a pentamethylene radical, with the exception of glyceryl tri-(di-n-propylacetate). These esters are useful in the treatment of central nervous system disorders and including, in particular, convulsive states and seizures, and disorders relating to the field of neuropsychiatry.

347041

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