Polyol/oil suspensions for the sustained release of proteins

Details Polyol/oil suspensions for the sustained release of proteins Polyol/oil suspensions for the sustained release of proteins

A - Human Necessities

61

K

A61K 9/10 (2006.01) A61K 47/00 (2006.01) A61K 47/10 (2006.01) A61K 47/12 (2006.01) A61K 47/26 (2006.01) A61K 47/44 (2006.01)

Patent

CA 2355618

The present invention relates to the preparation of polyol/thickened oil suspensions containing a biologically active agent, for the sustained delivery of the biologically active agent. The described protein/glycerol/oil suspensions show sustained release of protein, e.g., G-CSF, of up to at least one week.

La présente invention concerne la préparation de suspensions d'huile épaissie/polyol contenant un agent biologiquement actif devant être administré selon une libération prolongée. Les supensions de protéine/glycérol/huile montrent la libération lente de la protéine, par exemple, la G-CSF pendant au moins une semaine.

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