Polyoxyalkylene glycol gelatin capsule fill formulations...

Details Polyoxyalkylene glycol gelatin capsule fill formulations... Polyoxyalkylene glycol gelatin capsule fill formulations...

F - Mech Eng,Light,Heat,Weapons

42

B

F42B 12/40 (2006.01) A61K 8/11 (2006.01) A61K 8/39 (2006.01) A61K 8/81 (2006.01) C09B 67/08 (2006.01) C09B 67/20 (2006.01) F42B 12/76 (2006.01)

Patent

CA 2296016

Disclosed are fill compositions suitable for carrying pigment and encapsulation within gelatin capsules comprising: (a) a polyoxyalkylene glycol having a mean molecular weight of from about 200-500; (b) glycerol; (c) water; (d) an oleaginous material; (e) a carboxylic copolymer; and (f) a neutralizing agent for the carboxylic polymer in an amount effective to neutralize at least about 75 % of the carboxylic acid groups on the polymer. Also disclosed are gelatin capsules containing such compositions and methods for preparing the fill compositions.

Cette invention se rapporte à des compositions de remplissage conçues pour le transport de pigments et à l'encapsulation de telles compositions dans des capsules de gélatine. Ces compositions contiennent: (a) un polyoxyalkylèneglycol ayant une masse moléculaire comprise entre 200 et 500; (b) du glycérol; (c) de l'eau; (d) une matière oléagineuse; (e) un copolymère carboxylique et (f) un agent neutralisant destiné au polymère carboxylique, en quantité suffisante pour neutraliser au moins 75 % environ des groupes d'acide carboxylique sur le polymère. Cette invention se rapporte à des capsules de gélatine contenant de telles compositions et à des procédés de préparation de ces compositions de remplissage.

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