C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 43/11 (2006.01) A61K 31/765 (2006.01) A61K 31/77 (2006.01) A61K 45/06 (2006.01) A61K 47/48 (2006.01) C07C 43/178 (2006.01) C08G 65/08 (2006.01) C08G 65/26 (2006.01) C08G 65/30 (2006.01)
Patent
CA 2106474
The present invention comprises novel preparations of polyoxypropylene/polyoxyethylene copolymers which retain the therapeutic activity of the commercial preparations, but are substantially free from the undesirable effects which are inherent in the prior art preparations. The preparation entails first condensing propylene oxide to produce a polyoxypropylene polymer and then condensing ethylene oxide with the polyoxypropylene polymer to produce a polyoxypropylene/polyoxyethylene block copolymer of the general formula: HO(C2H4O)b(C3H6O)a(C2H4O)b H wherein a and b are integers. Because the preparations of polyoxypropylene/polyoxyethylene copolymers which comprise the present invention are a less polydisperse population of molecules than the prior art polyoxypropylene/polyoxyethylene copolymers, the biological activity of the copolymers is better defined and more predictable. The polydispersity of the copolymer is very low, average less than 1.07.
Culbreth Paula H.
Emanuele R. Martin
Hunter Robert L.
Cytrx Corporation
Finlayson & Singlehurst
LandOfFree
Polyoxypropylene/polyoxyethylene copolymers with improved... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Polyoxypropylene/polyoxyethylene copolymers with improved..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polyoxypropylene/polyoxyethylene copolymers with improved... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1650072