Polypeptide

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/10 (2006.01)

Patent

CA 2574770

The present invention relates to a novel polypeptide chain forming a particular 3 dimensional fold characterised by a .beta.-sandwich. By altering the amino acid sequence in specific regions of the polypeptide of the invention novel binding characteristics are developed. Methods for the generation of a polypeptide according to the invention and uses of polypeptides of the invention are also described.

La présente invention a trait à une nouvelle chaîne polypeptide formant un repliement tridimensionnel caractérisé par un sandwich .beta.. Grâce à la modification de la séquence d'acides aminés dans des régions spécifiques du polypeptide de l'invention de nouvelles caractéristiques de liaison sont développées. L'invention a également trait à des procédés pour la génération d'un polypeptide selon l'invention et aux utilisations des polypeptides de l'invention.

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