Polypeptide and protein derivatives and process for their...

Details Polypeptide and protein derivatives and process for their... Polypeptide and protein derivatives and process for their...

C - Chemistry, Metallurgy

07

K

167/139, 530/5.0

C07K 14/00 (2006.01) A61K 38/00 (2006.01) A61K 38/28 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/08 (2006.01) A61K 51/10 (2006.01) C07K 14/62 (2006.01) C07K 16/00 (2006.01) G01N 33/531 (2006.01)

Patent

CA 1341053

Protein and polypeptide derivatives and their salts are claimed characterized in that a protein or polypeptide is conjugated via an intermediate grouping containing at least one radical of the formula -C(R)=N- (or -N=C(R)-) or -CH(R)-NH- (or -NH-CH(R)-), wherein R is hydrogen or a hydrocarbon residue which may be substituted, with the same or a different protein or polypeptide, with a reporter group or a cytotoxic agent as well as a process for their preparation and the novel intermediates therefor.

535860

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