Polypeptide compounds for inhibiting angiogenesis and tumor...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 16/28 (2006.01)

Patent

CA 2559554

In certain embodiments, this present invention provides polypeptide compositions (e.g., antibodies and antigen binding portions thereof that bind to EphB4), and methods for inhibiting EphB4 activity. In other embodiments, the present invention provides methods and compositions for treating cancer or for treating angiogenesis-associated diseases.

Dans certains modes de réalisation, l'invention concerne des compositions polypeptidiques ainsi que des procédés d'inhibition de l'activité d'EphB4. Dans d'autres modes de réalisation, l'invention porte sur des procédés et sur des compositions pour le traitement du cancer ou de maladies associées à l'angiogenèse.

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