Polypeptide conjugates for transporting substances across...

A - Human Necessities – 61 – K

Patent

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A61K 47/48 (2006.01)

Patent

CA 2252706

Polymeric compositions effective for delivering compounds in living organisms are described. The compositions include polypeptides which exhibit solubility in both hydrophilic and lipophilic environments by undergoing a reversible pH- dependent transition from a low-pH, lipophilic form to a high-pH, hydrophilic form.

Compositions polymères permettant l'apport efficace de composés dans des organismes vivants. Les compositions comprennent des polypeptides présentant une solubilité dans des environnements à la fois hydrophiles et lipophiles du fait qu'ils subissent une transition réversible dépendante du pH d'une forme lipophile à pH bas à une forme hydrophile à pH élevé.

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