Polypeptide from horseshoe crab exhibiting affinity for...

Details Polypeptide from horseshoe crab exhibiting affinity for... Polypeptide from horseshoe crab exhibiting affinity for...

C - Chemistry, Metallurgy

07

K

530/7.08, 530/1.

C07K 7/08 (2006.01) C07K 1/14 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1337781

Disclosed is a novel polypeptide represented by the formula: (1) Image wherein Lys represents lysine, Trp tryptophan, Cys cysteine, Phe phenylalanine, Arg arginine, Val valine, Tyr tyrosine, Gly glycine, Ile isoleucine and X a hydroxyl group or an amino group, its analogue and a method for preparing the same. The polypeptide exhibits strong affinity for lipopolysaccharide, and is useful for removing endotoxin and as a therapeutic agent for bacterial infections.

575083

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