C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) C07K 14/36 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2327264
A peptide K97-0003 which exerts an anti-HIV activity through the inhibition of the formation of syncytia by human immunodeficiency virus (HIV) envelope glycoprotein together with host cells wherein a receptor to the HIV is expressed. This peptide has been found out by studies for discussing novel substances having an HIV inhibitory activity and being efficacious in treating AIDS. The base sequence of a gene encoding the polypeptide and a process of producing the polypeptide by using a strain K97-0003.
L'invention concerne un peptide K97-0003 exerçant une action anti-VIH dans la mesure où il inhibe la formation de syncytium par la glycoprotéine d'enveloppe du virus de l'immunodéficience humaine (VIH) et par des cellules hôtes dans lesquelles un récepteur du VIH est exprimé. Ce peptide a été découvert lors d'études portant sur de nouvelles substances qui inhibe le VIH et permettent de lutter efficacement contre le SIDA. L'invention concerne également la séquence de bases d'un gène codant pour ce polypeptide, ainsi qu'un procédé de production de ce polypeptide à l'aide d'une souche K97-0003.
Ohmura Satoshi
Tanaka Haruo
Gakkou Houjin Kitasato Gakusen
Japan Society For The Promotion Of Science
Kiim Pharm Lab. Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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